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CH435/535

CRN 35616, 35617


Structure Determination by Spectrosciopic Methods

Dynamic Behavior Measured by NMR (Part 2)

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We saw previously a broadening of lines in cyclododecatriene. Molecular mechanics reveals a group of low-energy conformers:


CDT_1.pdb

CDT_2.pdb

CDT_3.pdb

CDT_4.pdb

In this example, the spectroscopic problem may be too challenging if we cool the sample, and simply raising the temperature becomes the preferred solution to simplifying the spectrum.
Room temperature:


35° C:


45° C:

55° C:
65° C:
75° C:

85° C


Last updated: 9/22/2018