Final Exam CH 130 Name ________________________
June, 2001 ID # _____________________
There are 7 pages and 38 questions on this exam. Be sure you have them all.
Write your answers to the 3 questions on this page below and tear the page off before turning it in.
Answer the multiple choice questions on the Scantron sheet. Each of the multiple choice problems is worth 2.5 points.
1. Using your “memorized” amino acids, draw a tripeptide containing 3 different amino acids (complete structures but don’t worry about bond angles). Identify the peptide bond(s).
2.5 pts
2. Explain what reaction cysteine can undergo that no other amino acid can either by words or by showing the reaction:
2.5 pts
3. Describe and give the family names of four (4) distinctly different types of polymers we have studied. Provide enough detail to show that you understand the basic structures of the polymers (you do not need to have all details correct for the molecular structure of the polymers). You may describe the polymerization process that creates each polymer if that helps you describe the structure. Hint: if you look back over this exam, at least 5 different polymer types are mentioned.
7.5 pts
4. Which type of dye would be expected to rub off the fabric easiest?
A. Vat dyes (such as indigo)
B. Acid dyes
C. Basic dyes
D. Reactive dyes
E. All are equivalent
5. In the molecule shown to the right, the number of C atoms is ______
and the number of H atoms is _______.
A. 6, 12
B. 9, 14
C. 10, 12
D. 10, 18
E. None of these
6. Which of the following statements regarding the Amylases and Starch experiment is the most accurate description of the experiment?
A. The blue color is used to tell when the reaction solution is still basic (alkaline).
B. The amylase creates starch from sugar in the multi-well tray.
C. The breakdown of starch occurs in the multi-well tray.
D. The amylase creates starch from sugar in the dropper being held in the fingers.
E. The breakdown of starch is occurring in the dropper being held in the fingers.
7. A mutation involves an error in
A. mRNA manufacture
B. translation
C. tRNA manufacture
D. DNA replication
E. transesterification
8. The functional group illustrated by the molecule shown to the right is
A. alcohol B. amide C. ether D. ester E. amine
9. What is the IUPAC name of the compound CH3-CH2-OOCCH3 ?
A. 2-butanoic acid
B. 3-butanoic acid
C. ethyl ethanoate
D. propyl methanoate
E. methyl propanoate
10. When an alkene reacts with an element from group 7A (the halogens), the reaction is referred to as
A. combustion
B. decomposition
C. displacement
D. addition
E. oxidation
11. The polymer formed from CH2=CHCH3 will have the structure of
A. a long string of CH2 groups joined by carbon-carbon single bonds
B. as in answer A except every other C will have a CH3 group as a side group
C. as in answer A except every C will have a CH3 group as a side group
D. a long string of CH groups joined by carbon-carbon double bonds
E. a long string of CH groups joined by alternating carbon-carbon single and double bonds
12. Which of the following is the least soluble in water?
A. diethyl ether B. methyl acetate C. 1-butanol D. 1-decanol E. n-decane
13. All the following are true concerning a three-carbon ketone EXCEPT
A. Its condensed formula is CH3-CO-CH3
B. Its systematic name is propanone
C. Its common name is acetone
D. Its structural formula is shown to the right:
E. It has a higher boiling point than a carboxylic acid of similar molecular weight
14. Aldehydes and ketones are similar in all the following properties EXCEPT
A. solubility in non-polar solvents
B. small ones are soluble in water
C. flamability
D. susceptibility to further mild oxidation
E. tendency to have strong, often pleasant odors
15. The symbol [O] written above a reaction arrow means
A. oxygen is removed from one of the reactants during the reaction
B. the reaction consumes oxygen from the atmosphere
C. that an oxidation is occurring
D. that a reduction reaction is occurring and oxygen is liberated
E. None of the above
16. In the tetrapeptide Ala∙Cys∙Val∙Leu, the C-terminal amino acid is ____
and the N-terminal amino acid is ____.
A. Ala, Leu B. Cys, Val C. Leu, Ala D. Val, Cys E. None of these
17. Which of the following compounds is an example of an amine salt?
A. B. C.
D. E.
18. Pick the best statement
A. Structural isomers have the same molecular formula but different connections
B. Cis- and trans- isomers are not structural isomers because the connections of the atoms are the same
C. The two optical isomers of a chiral bio molecule behave differently because enzyme active sites are generally chiral
D. Ala∙Phe and Phe∙Ala are examples of structural isomers
E. All of these are true
19. In RNA, U replaces the T used in DNA. An RNA sequence complementary to C-G-G-T-T-A-G in DNA is
A. G-C-C-A-A-T-C
B. C-G-G-T-T-A-G
C. A-T-T-G-G-C-T
D. G-C-C-A-A-U-C
E. G-C-C-U-U-A-C
20. Which molecule is not an isomer of the molecule CH3-O-C2H5 ?
A. CH3-O-CH2CH3
B. C3H7OH
C. CH3CH2OCH3
D. CH3CH(CH3)OH
E. CH3CH(OH)CH3
21. Which of the following is true for geometric (cis-trans) isomerism?
A. Each carbon must have four different groups bonded to it
B. Each of the two double-bonded carbons must have 2 different groups on it
C. Only one of the two double-bonded carbons must have 2 different groups on it
D. A total of four different groups must be found on the double-bonded carbons
E. Geometric isomers are not true isomers because they slowly interconvert.
22. The amino acid sequence of a protein is known as its ________________
A. primary structure
B. secondary structure
C. tertiary structure
D. quaternary structure
E. None of the above
23. All of the following interactions are important in maintaining the tertiary structure of a protein EXCEPT
A. hydrophobic interactions
B. hydrogen bonding within the backbone
C. disulfide bridges
D. salt bridges
E. phosphodiester bonds
24. A zwitterion is:
A. a molecule that has both a positive and a negative charge
B. a molecule that is negatively charged
C. a molecule that is positively charged
D. a molecule that has no charges
E. the answer depends upon the pH of the solution
25. When a protein is ____, its primary structure is destroyed, thus destroying the other aspects of its structure.
A. denatured B. polymerized C. ionized D. hydrolyzed E. esterified
26. The primary difference between a virus and a retrovirus is
A. a virus has no protein coating but a retrovirus does have a protein coating
B. a retrovirus undergoes reverse transcription to form DNA that can make more of the retrovirus
C. a virus can replicate on its own
D. a retrovirus can replicate on its own
E. there is no real difference (that is, “retro” is just a new term for the same thing).
27. Enzymes are members of which class of bio molecules?
A. carbohydrates B. lipids C. nucleic acids D. proteins E. steroids
28. Identify which of the carbons labeled A, B, C, or D in the molecule below is chiral:
29. Place in order of decreasing molecular weight: a. tRNA, b. gene c. mRNA d. DNA e. vitamin
A. a > b > c > d > e B. d > b > c > a > e C. e > d > c > b > a D. d > b > a > c > e
30. Which factor is NOT important in explaining how enzymes work?
A. Two different substrate molecules are brought into close contact
B. Substrates are placed near acidic or basic sites
C. The bonds in substrates are subjected to strains which weaken them
D. Substrates are forced into the correct orientation for interaction
E. Enzymes are a source of vitamins needed to react with substrates
31. Which of the following is a major function of nucleic acids?
A. long term storage of energy
B. storage and intracellular transfer of energy
C. catalysis of virtually all biochemical reactions
D. structural support in both plants and animals
E. storage and transfer of genetic information
32. The backbone of a nucleic acid molecule consists of
A. alternating sugar and nitrogen base groups linked by amide bonds
B. alternating sugar and phosphate groups linked by phosphate ester bonds
C. alternating nitrogen bases and phosphate groups linked by amide bonds
D. sugar molecules bonded from the #3 carbon of one molecule to the #5 carbon of the other by glycosidic linkages
E. complementary bases joined by hydrogen bonds
33. All of the following statements about RNA are true EXCEPT
A. RNA can exist in the three forms: rRNA, tRNA, and mRNA
B. RNA molecules are smaller than DNA molecules and form double helices like DNA
C. RNA does not contain thymine (T)
D. Transfer RNA delivers amino acids to the protein chain as it is being manufactured
E. Messenger RNA is complementary to the template strand of its DNA and contains the essential sequence information from the gene
34. Which of the following is an example of a tertiary amine?
A.
B.
C.
D. E.
35. The process in which information from DNA is used to guide the manufacture of RNA is called
A. mutation B. translocation C. transcription D. translation E. replication
36. Pick the most accurate statement.
A. Nucleic acids and proteins have similar structures in that both consist of an unchanging, repeating backbone.
B. All living systems contain proteins, but plants and animals do not use the same set of amino acids.
C. Nucleic acids and proteins are built from the same small set of amino acids.
D. DNA is taken apart nucleotide by nucleotide to build the proteins a living system requires.
E. Plants and mammals both contain DNA, but plants use carbohydrates instead of proteins.
37. One of the main reasons for using recombinant DNA techniques is
A. circular DNA loops are more symmetrical than the double helix.
B. to improve upon the accuracy of building the desired proteins
C. to improve upon the speed of building the desired proteins.
D. to create DNA without genetic defects.
E. to create DNA that is better at dealing with radiation damage.
38. All of the following are functions of proteins EXCEPT
A. transport of necessary chemicals
B. protection against foreign substances
C. movement
D. control of biochemical reactions
E. storage of genetic information