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Dr. Remcho received his BS in biochemistry in 1989 and his Ph.D. in chemistry (with Prof. Harold McNair) in 1992 at Virginia Tech. He was an Associated Western Universities NW Postdoctoral fellow with Professor J. Calvin Giddings at the University of Utah and Dr. Nathan Ballou at the Pacific Northwest National Laboratory. Currently he is Professor of Chemistry and of Materials Science, and adjunct Professor of Biochemistry & Biophysics at Oregon State University. He is a founding member of the Oregon Nanoscience and Microtechnologies Institute (ONAMI). His research group focuses on the design, modeling and optimization of microscale analytical and reaction systems and the application of these systems in biochemical, environmental, and nanomanufacturing problem solving. He is a National Science Foundation CAREER award recipient and has been recognized for teaching excellence. He has numerous publications in the field of analytical chemistry.
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Myra Koesdjojo
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Myra received her Ph.D. in Analytical Chemistry with a focus in fabrication of microfluidic devices. She has developed a series of fabrication techniques capable of producing polymer-based microfluidic devices. Myra uses a variety of polymer materials including PMMA, PC, polyetherimide (PEI), polysulfone (PSU), poly(ethylene terephthalate) (PETE), in microchip fabrication. Myra’s fabrication method utilizes a two-stage embossing process to create the microchannels followed by vaporized solvent welding for sealing the microchips. Microchips of many different designs have been built using her technique. Said microchips have been used to perform several analyses, including chromatographic separations, quantitative indicator assay, and biomolecule assay.
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Yolanda is currently exploring microfluidic devices for medical diagnostics. Her focus is on developing the synthesis of antibody-conjugated magnetic nanoparticles as well as demonstrating its application. The simultaneous extraction and separation of clinically important drugs utilizing the synthesized particles in a novel lab-on-a-chip device is one example. Yolanda is also actively working on developing new methods for fabrication of microfluidic devices. Miniaturization and integration of a total analysis system are of special emphasis.
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Taehyeong’s work utilizes microchips for separation. He is currently focusing on the development of a solvent-resistant, nanofiltration membrane to separate synthesized nanoparticles by size. Said membrane will reject particles and dissolved molecules bigger than molecular weight cut-off (MWCO), permeate solvent and molecules smaller than MWCO. The benefits of a solvent resistant nanofiltration membrane are that the device will function using less energy and will allow separations based on the molecular weight. Microfluidic devices with nanofiltration membranes allow for minimization of solvents and time, as well as a higher yield and narrower distribution of nanoparticles. Taehyeong’s will interface an upstream microreactor with the extractor utilizing the nanofiltration membrane to optimize the synthesis process of nanoparticles.
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Jintana’s research is toward the development of a microfluidic device for separation. She has developed a new method for heavy metals extraction from drinking water using a spiropyran modified PMMA microchip as a photoactivable microfluidic device. The catch and release of metal ions on the spiropyran modified stationary phase are controlled by UV/visible irradiation. The ultimate goal is the development of a heavy metal specific, chip-based version, of this “catch and release” chemistry for development in the field. The microchip will function most remarkably in the analysis and remediation of ground water.
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Esha’s work involves development of microfluidic devices for biomolecule detection. Her work includes development of methods for selective patterning of bioelements on various sensor substrates as well as the modification of nanoparticle surfaces to be used as labels or as a solid phase for immunoassays. Esha is currently working on the biofunctionalization of silica surfaces with biomolecules such as proteins, antibodies and biotin. Microcontact printing, photolithography aided patterning and photo-activated patterning are some of the methods used for selective patterning of surfaces.
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Kelsie Warner
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Kelsie is an undergraduate researcher in the Department of Chemistry. Her research career began Fall Term of her sophomore year. She will use her research to fulfill the thesis requirement for the University Honors College in which she is enrolled. She has worked on various projects in the areas of surface modification, fabrication and analysis of microfluidic devices. Kelsie is currently working on developing a microfluidic device that will facilitate research in the field of molecular biology.
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Saki Kondo
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Saki is currently an exchange student in the Remcho group at Oregon State University. Her research interests include fabrication of microfluidic devices and surface modifications on microfluidic chips.
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Alumni:
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Corey Koch, Ph. D.
Current position: Post Doc., Web labs, Philomath OR |
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Jack Rundel, Ph.D.
Current position: Research Associate, Microproducts Breakthrough Institute |
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Daniela Hutanu, Ph.D.
Current position: Invitrogen
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Carlos Gonzalez, Ph.D.
Current position: Post Doc., Colorado State University -Fort Collins
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Bin Cao, M.S.
Current position: |
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Gabriela Chirica, Ph.D.
Current position: Research Scientist, Sandia National Laboratory (Livermore, CA) |
Michael Cipoletti, M.S.
Current position: Forensic Chemist, Pennsylvania State Crime Lab |
Stacey Clark, Ph.D.
Current position: Research Scientist, International Flavors and Fragrances, NJ |
Angela Doneanu, Ph.D.
Current position: Researcher, OSU |
Patricia Latzo, M.S.
Current position: Research Scientist, Mylan Pharmaceuticals |
Laura Lessard, M.S.
Current position: Ph.D. Program, University of Vermont, Burlington |
Daming Li, M.S.
Current position: Ph.D. candidate, WVU |
Preston Lowe, M.S.
Current position: Forensic Chemist, FBI |
Jessica Tan, Ph.D.
Current position: Research Chemist, Wyeth-Ayerst Pharmaceuticals |
Patrick Vallano, Ph.D.
Current position: Research Chemist, Merck Pharmaceuticals |
Todd Vanyo, M.S.
Current position: Environmental Chemist, Minnesota |
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