BRG Meeting Archive: 2007
date hot topic research problem
12-12-07
2nd Annual BRG Symposium
10:00 am Opening remarks
Paul
10:10 am Axially Chiral Ambifunctional Catalysis: In pursuit of Axial Asymmetric Induction
Mark
10:45 am Studies Toward a Practical Synthesis of Thebaine
Mike
11:20 am Broadening the Scope of the Modified-Julia Alkenation: A Mild and Selective Method for the Synthesis of (Z)-Configurated alpha,beta-Unsaturated Lactones
Heath
11:55 am Synthesis of (±)-Sparteine from a Tetraoxobispidine Core
John
12:30 pm Lunch at American Dream Pizza  
2:00 pm Catalytic Asymmetric Desymmetrization of D2d-Symmetric Biaryl Compounds: A Tale of Two Substrates
J.
2:35 pm Lone-pair/Lone-pair Proximity Effects in a Series of Tethered 8,8´-Biquinolyls
Selena
3:10 pm Spanning the Gap: Two Generations of Carbenoid Homologation as Applied to Synthesis
Chris
3:45 pm Enantioselective Phase-Transfer Catalysis with Quaternized 8,8’-Biquinolyl Cations
Chao
4:20 pm State of the BRG address and concluding remarks
Paul
         
12-06-07 Cyclo-propenes & -propanes Heath    
[LINK] Gevorgyan, BH-type rxn: JACS 2007, 129 (48), 14868.  
[LINK] Fox, methylenecyclopropane synth.: ACIE 2006, 45 (24), 3960.  
[LINK] Bach, strain-energy: JACS 2004, 126 (13), 4444.  
         
11-21-07 Thanksgiving "meeting"      
         
11-14-07     Hoffmann Chris
     
profile papers: [1 2 3 4 5]
         
11-07-07 Mixed organo/metal catalysis Selena    
[LINK] Saicic, proline/Pd-cat.: OL 2007, ASAP (10-24-07).  
[LINK] Wu, proline/Ag(I)-cat.: OL 2007, ASAP (10-26-07).  
[LINK] Córdova, Pd-cat. Trost-Tsuji rxns: ACIE 2006, 45 (12), 1952.  
         
10-31-07     Buchwald J.
     
profile papers: [1 2 3 4 5]
         
10-24-07 New benzannulations John    
[LINK] Zhang, via Au(I)-cat.: OL 2007, 9 (22), 4627.
problem answer(s): [1]
[LINK] Quayle, via ATRC: ACIE 2007, 46 (11), 1869.  
[LINK] Serra, via dienylketenes: Chem. Eur. J. 2007, 13 (24), 6782. (mini-review)
         
10-17-07     Hudlicky Mike
     
profile papers: [1 2 3 4 5]
     
problem answer(s): [1]
         
10-10-07     Oppolzer Mark
     
profile papers: [1 2 3 4 5]
         
10-03-07 Papers from upcoming speakers Chao    
[LINK] Brummond, allene cyclizations: OL 2007, 9 (2), 347.  
[LINK] Williams, carbinolamide synth: TL 2007, 48 (42), 7456.  
[LINK] Hsung, atropselective synth: OL 2007, 9 (20), 3969.  
         
09-26-07     Lautens Heath
     
profile papers: [1 2 3 4 5]
         
09-05-07 Magnesium carbenoids Chris    
[LINK] Satoh, Chem. Soc. Rev. 2007, 36 (10), 1561.    
         
08-29-07     Myers Selena
     
profile papers: [1 2 3 4 5]
         
08-22-07 New methods from Boston J.    
[LINK] Fu, alkyl-alkyl Suzuki coupling: JACS 2007, 129 (31), 9602.  
[LINK] Evans, asymm. propargyl silane add.: JACS 2007, 129 (31), 9606.  
[LINK] Hoveyda, asymm. olefin metathesis: OL 2007, 9 (15), 2871.  
         
08-15-07     Comins John
     
profile papers: [1 2 3 4 5]
         
08-08-07 Two recent syntheses of morphine Mike    
[LINK] Fukuyama: OL 2006, 8 (23), 5311.    
[LINK] Trost: JACS 2002, 124 (49), 14542.    
         
08-01-07 Catalysis by thioureas Mark    
[LINK] List, nitroolefin reduction: JACS 2007, 129 (29), 8976.  
[LINK] Asymm. Baylis-Hillman (mini-review): ACIE 2007, 46 (25), 4614.
[LINK] Sibi, conjugate add. of amines: JACS 2007, 129 (26), 8064.
         
07-25-07     Kobayashi Chao
     
profile papers: [1 2 3 4 5]
         
07-18-07 Amination by "CH" activation Heath    
[LINK] Driver, Rh(II)-nitrenoid C-H insertions: JACS 2007, 129 (4), 7500.
[LINK] Shi, allylic/homoallylic diamination : JACS 2007, 129 (4), 7497.  
[LINK] Savarin, oxime C-H insertion: OL 2007, 9 (6), 981.  
         
06-27-07     Johnson Chris
     
profile papers: [1 2 3 4 5]
         
06-13-07 Lithiation: mechm & appln Selena    
[LINK] Hoppe, enantiosel. lithiation in allene synthesis: ACIE 2007, 46 (17), 3131.
[LINK] Reich, rxn rates from RLi aggregates: JACS 2007, 129 (12), 3492.
[LINK] Collum, mechm. of ortholithiation: JACS 2007, 129 (8), 2259.  
         
05-30-07 Advances in aromatic chemistry J.    
[LINK] Chauvin, a "carbobenzene" derivative: ACIE 2007, 46 (23), 4337.
[LINK] Borden, bishomoarom. in bullvalenes: JOC 2005, 70 (7), 2627. (+ see [LINK])
[LINK] Freeman, homoarom. in heterocycles: JOC 2005, 70 (6), 1998.  
  Problems with DFT functionals Paul    
[LINK] Schreiner: ACIE 2007, 46 (23), 4217. (+ see [LINK])  
         
05-16-07     Westheimer Mike
     
profile papers: [1 2 3 4]
         
05-09-07 Advances in epoxide chemistry John    
[LINK] Williams, dispiroepoxides: JACS 2007, 129 (9), 2438.
[LINK] Hodgson, cycloprop. via metalated epoxides: JACS 2007, 129 (14), 4456.
[LINK] Hodgson, review: Pure & Appl. Chem. 2007, 79 (2), 269. (in library at QD1.P8)
         
05-02-07 Synthesis challenge tactics meeting      
         
04-25-07 Advances in organocatalysis Chao    
[LINK] MacMillan, SOMO activation: Science ASAP March 29, 2007 (+ see [LINK])
[LINK] Johnston, "chiral proton" catalysis: JACS 2007, 129 (12), 3466.
[LINK] Bode, NHC cat. cyclopentene formation: JACS 2007, 129 (12), 3520.
         
04-18-07     Aggarwal Mark
     
profile papers: [1 2 3a 3b 4 5]
         
04-11-07     Breslow Heath
   
profile papers: [1 2a 2b 3a 3b 4 5]
         
04-04-07 Advances in prebiotic chemistry Chris    
[LINK] Eschenmoser, ACIE 2007, 46 (14), 2478.  
[LINK] Sutherland, ACIE 2006, 45 (37), 6176 (+ see [LINK]).
[LINK] Ghadiri, JACS 2006, 128 (1), 20.  
         
03-14-07     Semmelhack Selena
     
profile papers: [1 2 3 4 5]
         
03-07-07     Kishi J.
     
profile papers: [1 2 3 4 5]
         
02-28-07 Decarboxylative coupling rxns Lei    
[LINK] Baudoin, decarb. biaryl coupling (highlight): ACIE 2007, 46 (9), 1373.
[LINK] Shair, decarb. aldol rxn: JACS 2007, 128 (5), 1032.
[LINK] Tunge, synth. homoallylic amines: JACS 2006, 128 (31), 10002.
  Quinine total synthesis Paul    
[LINK] Seeman, controversy or storm in a tea cup?: ACIE 2007, 46 (9), 1387.
         
02-21-07     Barrett John
     
profile papers: [1 2 3 4 5]
         
02-14-07     Curran Chao
     
profile papers: [1 2 3 4 5]
         
02-07-07 Three-component coupling rxns Mark    
[LINK] Rovis, Sakurai-Prins-Ritter sequence: JACS 2006, 128 (51), 16480.
[LINK] Saito, Ni-cat. [3+2+2] co-cyclization: ACIE 2006, 45 (15), 2446.
[LINK] Kerr, homo [3+2] cycloadd.: OL 2004, 6 (1), 139 (+ see application [LINK]).
         
01-31-07 Advances in organoazide chemistry Heath    
[LINK] Lutz, click-chemisty mini-review: ACIE 2007, 46 (7), 1018.  
[LINK] Banert, tetraazidomethane: ACIE 2007, 46 (7), 1168.  
         
01-24-07     Leonard Chris
         
01-18-07 Vitamin B12 chemistry Selena    
[LINK] Kräutler, methylation: ACIE 2000, 39 (2), 393.
[LINK] Dowd, skeletal rearrangements: JACS 1998, 120 (6), 1133 (+ see Rooney [LINK]).
[LINK] van der Donk, reductive dehalogenation: Chem. Commun. 2006, (5), 558.
         
01-09-07 Recent group 9 metal cat. rxns. J.    
[LINK] Yorimitsu, Co-cat. alkenylation: JACS 2006, 128 (24), 8068.
[LINK] Krishe, Rh-cat. dienylation: JACS 2006, 128 (50), 16040.
[LINK] Williams, Ir-cat. alchol to amide conversion: OL 2007, 9 (1), 73.
 
 
         
       
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Last modified: August 6, 2009 (PRB)